If you already are taking T4 because of a thyroid problem, sticking with the dosage is a good idea. Normal TSH levels are between 0.3 – 6 (miBambunits/mL). The oral version, should be taken in the AM (when the stomach is completely empty) 30-60 minutes before eating. You probably already know this. It is highly protein bound 99.97% and the half life is 7 days. Hormone levels remain very steady which means once a day dosing is fine. But, it takes 1 month to reach a plateau (therapeutic level).
Substances that reduce absorption:
Histamine (H2) such as -tagament
Proton Pump Inhibitors -Prevacid
Sucralfate -Carafate
Cholestyramine -Questran
Colestipol -Colestid
Antacids contaiing aluminum -maalox, mylanta
calcium supplements-Tums, Os-cal ***(Note: T4 reduces calcium which can lead to bone loss).
Iron Supps -ferrous sulfate
Magnesium Salts
Orlistat
IV doses are about 50% of the oral dose.
***T3 is the one with a short half-life, shorter duration of action and rapid onset. It is often taken 2x day.
As a future medical profession, I must say that both of these are dangerous and I would never take them. As a member of the forum, I respect the thoughts of other members, particularly those who have the experience with this that I do not and never will. If one is considering taking either T3 or T4, it should be well researched from the standpoint of "How do I not hurt myslef?" Instead of, "how do get what I want?"
Originally Posted by Quester