Not so popular anabolic steroids.

Here is a sneak peek at some obscure and not so obscure anabolic steroids that you most likely will never use do to lack of availably or extremely high cost or both.

Androisoxazole
17β-Hydroxy-17α-methylandrostano[3,2-c]isoxazole.

EST.A:A Ratio 30/320

Look familiar? What we have here is a DHT derivative that has a methyl-group in the 17th pos to allow oral dosing, in fact this drug is very closely related to stanozolol . The only difference is the group off the A-ring of androisoxazole (this protects the steroid) has an oxygen molecule instead of nitrogen in the additional ring. One would speculate this would be almost identical to stanozolol in effects, both good and bad.

Androisoxazole

Stanozolol

See the small change to the additional ring?

Bolasterone
17ß-Hydroxy-7a,17-dimethylandrost-4-en-3-one

A:A Ratio:300/575

This baby is briefly featured in Anthony Robert’s book The Ultimate Research Guide Vol.1. It’s a testosterone molecule with not one but two methyl-groups. One that’s most commonly found on most oral anabolics 17th also known as 17aa alkylation and the second methyl-group is in the 7th position this modification also increases oral bio-availability. Now if one methyl-group on testosterone was bad (methyl-testosterone) two would make this drug quite toxic. It’s a potent (bulking) steroid for sure and was highly popular in the 80s-90s before it was discontinued. It can be currently found in powder form.

Calusterone
17ß-Hydroxy-7ß,17-dimethylandrost-4-en-3-one

A:A Ratio:300/575

This is identical to the fore mentioned steroid bolasterone, the only difference is the methyl-group in the 7th position is pointing ‘up’ instead of ‘down’ like in bolasterone. This slight change (don’t ask me why) actually makes calusterone useful in the treatment of advanced breast cancer. Like its sister steroid it’s highly toxic.

Enestebol
4,17ß-Dihydroxy-17-methylandrosta-1,4-dien-3-one.

A:A Ratio: Est:0/100.

See that? It’s our good buddy methandrostenolone (D-bol) with a hydroxyl-group added to the 4th position. This molecular modification stops or greatly reduces 5a-reduction and aromatization of the patent hormone. This drug should not give any estrogenic or androgenic sides but would also significantly weaker than D-bol. In fact it’s basically just like T-bol and I think was released as a ‘Pro-hormone’.

Norclostebol
4-Chloro-17ß-hydroxyestr-4-en-3-one

A:A Ratio: N/A

Just nandrolone with an added chloro-group in the 4th. Norclostebol is to clostebol, what testosterone is to nandrolone, the parent hormone just missing that carbon atom in the 19th pos.

What I find very interesting about this particular drug is that although the 4-CL mod. stops aromatization and 5a reduction of the hormone making it ‘weaker’, the 5a reduced form of nandrolone (DHN) is actually a weaker anabolic/androgen than the parent hormone. One could speculate the 4-CL add on to the nandrolone would make it resistant to becoming a ‘weaker’ hormone giving it a higher anabolic/androgenic profile than nandrolone without the estrogen conversion.

Tiomesterone
1α,7α-Bis(acetylthio)-17β-hydroxy-17-methylandrost-4-en-3-one.

A:A Ratio: 61/456

This one is a real mystery to me. It’s an oral testosterone derivative. When I enquired about this compound I was told;
“ It’s a Di-Acetylthio derivative of 1alpha,7alpha,17beta-trihydroxy-17-methylandrost-4-en-3-one”

Ummm don’t worry I didn’t understand a word of that either. Studies do indeed show it’s useful for bodybuilding purposes though. One abstract is quoted saying Tiomesterone “was found to have exceptional anabolic properties”.

I first read about this steroid in an article by the chemist Patrick Arnold, you know that dude who brought 1-AD, AMP etc to the market? He also is accused of making THG as was but we’ll just sweep that under the rug. Anywayz. Right, were was I?

This steroid is kind of a cross between oxandrolone (5 alpha-androstan-2-oxa-17 alpha-methyl-17 beta-ol-3-one) and trenbolone (17-beta-hydroxyestra-4, 9-11-trien-3-one).

Oxatrebolone (you try coming up with a better name) (2 oxa-17-beta-acetoxy-estra-4,9,11-trien-3-one.)

This is basically trenbolone with the same modification that transformed DHT into oxandrolone.

PA says this drug has the same A:A ratio as nandrolone but is 5 times more powerful. Now i don’t know about you guys but this one defiantly spiked my interest. I believe (PA said the same) that if it was available it would be a rather expensive hormone due to the fact it’s a Var, tren , hybrid. Tren and Var are two pricey compounds in their own right.

11-fluoro-19-nor-dihydro-testosterone.

Nandrolone with a fluoro-group, it’s been shown too have a pretty good R.B.A of 73.5 (with metribolone having a RBA of 100) one of the cool properties off this drug is that it has low a uptake in the prostate, thus making this drug highly anabolic and without the risk of prostate growth.

They are many interesting anabolic steroids that were also left on the cutting room floor in the heyday of steroid research either because they were too androgenic (you wouldn’t want your sick daughter on tren would you?) or just too expensive to manufacture in bulk.

Many thanks to PhyChem on the Mind&Muscle.net forums for his help.

A:A Ratio: The androgenic (1st number) anabolic (2nd number) ratio of the hormone.

EST: Means it’s just a rough estimate of the A:A Ratio based off drugs that are similar.